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Learn to pronounce sub·stance

/ˈsəbstəns/
noun
  1. a particular kind of matter with uniform properties.
    "a steel tube coated with a waxy substance"
    synonyms: material, matter, stuff, medium, fabric
  2. the real physical matter of which a person or thing consists and which has a tangible, solid presence.
    "proteins compose much of the actual substance of the body"
    synonyms: solidity, body, corporeality, reality, actuality, materiality, concreteness, tangibility, density, mass, weight, shape, structure
  3. the quality of being important, valid, or significant.
    "he had yet to accomplish anything of substance"
  4. the essential nature underlying phenomena, which is subject to changes and accidents.

People also ask
a natural substance; This substance is so radioactive that it glows in the dark. This substance stretches to any shape you want.
subsTANCE from www.samhsa.gov
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noun · essence · nature · soul · manifestation · being · stuff · essentiality · aspect · quiddity · quintessence.